"Et tu, Brute?" is attributed to Julius Caesar during his assassination. However, historians debate whether he actually said anything. Some believe he may have uttered Greek phrases or nothing at all. Shakespeare coined the phrase, but the exact words
Constantinople, the capital of the Byzantine Empire, fell to the Ottoman Empire on May 29, 1453. This event marked the end of the Byzantine Empire and is considered one of the key events that signified the end of the Middle Ages.